PAPA NONOATE

CAS NO.：146672-58-4
Empirical Formula: C6H16N4O2
Molecular Weight: 176.22
MDL number: MFCD00801020
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-04 20:04:50

What is PAPA NONOATE?

Description

PAPA NONOate (146672-58-4) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of PAPA NONOate in 0.1 M phosphate buffer at pH 7.4 is 15 minutes at 37°C, or 77 minutes at room temperature.1?Dissociation is essentially instantaneous at a pH of 5.0.

The Uses of PAPA NONOATE

PAPA NONOate is an NO donor which suppresses the caspase apoptotic cascade.

What are the applications of Application

PAPA NONOate is an NO donor which suppresses the caspase apoptotic cascade

Definition

ChEBI: PAPA NONOate is an alkylamine.

References

1) Keefer?et al. (1996),?‘NONOates’ (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms; Methods Enzymol.,?268?281

Properties of PAPA NONOATE

Boiling point:	277.2±42.0 °C(Predicted)
Density	1.20±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in Water or Ethanol.
form	White to off-white solid.
pka	5.55±0.69(Predicted)
color	Off-white
Stability:	Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Solutions are not stable and must be prepared immediately before use.