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HomeProduct name listNOC-5

NOC-5

Synonym(s):3-(Aminopropyl)-1-hydroxy-3-isopropyl-2-oxo-1-triazene;3-[2-Hydroxy-1-(1-methylethyl)-2-nitrosohydrazino]-1-propanamine;NOC-5 - CAS 146724-82-5 - Calbiochem

NOC-5 Structural

What is NOC-5?

Description

NOC-5 is a stable nitric oxide (NO)-amine complex that acts as a NO donor. It can release two equivalents of NO in solution under physiological conditions without a cofactor. The half-life of NOC-5 in PBS (pH 7.4) is 93 minutes at 22°C, and it remains relatively stable in alkaline solution (pH ≥10.0).

Chemical properties

White Powder

The Uses of NOC-5

A stable NO-amine complex which can release NO spontaneously under physiological conditions. The half life of NO release in 0.1 M PBS at (pH7.4) at 37°C for 0.1mM NOC 5 is 25 minutes

The Uses of NOC-5

A stable NO-amine complex which can release NO spontaneously under physiological conditions. The half life of NO release in 0.1 M PBS at (pH7.4) at 37?C for 0.1mM NOC 5 is 25 minutes.

The Uses of NOC-5

Releases nitric oxide spontaneously in a rate-controlled manner; half life in solution = 93 min.

What are the applications of Application

NOC-5 is a nitric oxide (NO) donor relatively stable in alkaline solutions

Definition

ChEBI: NOC-5 is a nitroso compound that is triazane in which the nitrogen at position 1 is substituted by an isopropyl group and a 3-aminopropyl group, that at position 2 is substituted by a hydroxy group, and that at position 3 is substituted by an oxo group. It is a nitric oxide donor. It has a role as a nitric oxide donor. It is a nitroso compound, a tertiary amino compound and a primary amino compound.

Properties of NOC-5

storage temp.  -20°C
solubility  Water
form  White solid
color  White
Stability: Store at -20°C, Light and Moisture Sensitive

Safety information for NOC-5

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
GHS Hazard Statements H242:Self-reactive substances and mixtures; and Organic peroxides
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P234:Keep only in original container.
P235:Keep cool.
P240:Ground/bond container and receiving equipment.
P370+P378:In case of fire: Use … for extinction.
P403:Store in a well-ventilated place.

Computed Descriptors for NOC-5

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