2-Chloro-N,N-diethylacetamide

Synonym(s):2-Chloro-N,N-diethylacetamide;Chloroacetic acid diethylamide

CAS NO.：2315-36-8
Empirical Formula: C6H12ClNO
Molecular Weight: 149.62
MDL number: MFCD00000928
EINECS: 219-019-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

2-Chloro-N,N-diethylacetamide Structural

What is 2-Chloro-N,N-diethylacetamide?

Chemical properties

clear brown liquid

The Uses of 2-Chloro-N,N-diethylacetamide

2-Chloro-N,N-diethylacetamide has been used in:

preparation of calixarene amides
synthesis of 5-bromo-25,26,27,28-tetrakis[(N,N-diethylaminocarbonyl)-methoxy]calix[4]arene
synthesis of amide calix[4]pyrrole macrocycles with super-extended cavities
microwave-assisted organic synthesis of 3-cyano-N,N-diethyl-4-(4-methoxyphenoyl)-4-oxobutanamide

What are the applications of Application

2-Chloro-N,N-diethylacetamide is has been used in preparation of calixarene amides,synthesis of 5-bromo-25,26,27,28-tetrakis[(N,N-diethylaminocarbonyl)-methoxy]calix[4]arene, synthesis of amide calix[4]pyrrole macrocycles with super-extended cavities, and microwave-assisted organic synthesis of 3-cyano-N,N-diethyl-4-(4-methoxyphenoyl)-4-oxobutanamide.

What are the applications of Application

2-Chloro-N,N-diethylacetamide is mainly used in the synthesis of amides.

Properties of 2-Chloro-N,N-diethylacetamide

Melting point:	58 °C
Boiling point:	121-122 °C (12 mmHg)
Density	1.089 g/mL at 25 °C(lit.)
refractive index	1.469-1.471
Flash point:	>110°C
storage temp.	Store below +30°C.
solubility	85.5g/l
form	Liquid or Solid
pka	-0.95±0.70(Predicted)
Specific Gravity	1.089
color	Clear colorless to light yellow
Water Solubility	soluble
BRN	605866
CAS DataBase Reference	2315-36-8(CAS DataBase Reference)
NIST Chemistry Reference	Acetamide, 2-chloro-N,N-diethyl-(2315-36-8)
EPA Substance Registry System	Acetamide, 2-chloro-N,N-diethyl- (2315-36-8)

Safety information for 2-Chloro-N,N-diethylacetamide

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H302:Acute toxicity,oral H311:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H330:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.