Fmoc-Lys-OH hydrochloride
Synonym(s):Nα-Fmoc-L -lysine hydrochloride
- CAS NO.：139262-23-0
- Empirical Formula: C21H25ClN2O4
- Molecular Weight: 404.89
- MDL number: MFCD00190889
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-26 15:15:06
What is Fmoc-Lys-OH hydrochloride?
Description
Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used to synthesize antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also an alkyl chain-based PROTAC linker that can be used to synthesize PROTACs.
Chemical properties
White solid
The Uses of Fmoc-Lys-OH hydrochloride
It is used as an active pharmaceutical intermediate and in the synthesis of nε-(7-diethylaminocoumarin-3-carboxyl)- and nε-(7-methoxycoumarin-3-carboxyl)-l-fmoc lysine as tools for protease cleavage detection by fluorescence.
Properties of Fmoc-Lys-OH hydrochloride
| refractive index | -11.0 ° (C=1, DMF) |
| storage temp. | 2-8°C |
| solubility | Soluble in dimethyl formamide (0.3g in 2ml). |
| form | powder to crystal |
| color | White to Almost white |
| BRN | 8663370 |
| CAS DataBase Reference | 139262-23-0(CAS DataBase Reference) |
Safety information for Fmoc-Lys-OH hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Fmoc-Lys-OH hydrochloride
| InChIKey | MVMZFAIUUXYFGY-FYZYNONXSA-N |
| SMILES | C(C1C2=CC=CC=C2C2C=CC=CC1=2)OC(=O)N[C@H](C(=O)O)CCCCN.Cl |&1:18,r| |
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product: 139262-23-0 Fmoc-Lys-Oh Hcl 98%
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