Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listN-Succinimidyl 6-maleimidohexanoate

N-Succinimidyl 6-maleimidohexanoate

Synonym(s):N-(ε-Maleimidocaproyloxy)succinimide;N-Succinimidyl 6-maleimidocaproate;6-Maleimidocaproic acid N-succinimidyl ester;EMCS

  • CAS NO.:55750-63-5
  • Empirical Formula: C14H16N2O6
  • Molecular Weight: 308.29
  • MDL number: MFCD00043043
  • EINECS: 637-238-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-09-04 15:51:00
N-Succinimidyl 6-maleimidohexanoate Structural

What is N-Succinimidyl 6-maleimidohexanoate?

Description

Mal-heptanoic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Chemical properties

White to cream colored crystals

The Uses of N-Succinimidyl 6-maleimidohexanoate

6-Maleimidohexanoic acid N-hydroxysuccinimide ester can be used in:

  • Synthesis of maleimide-activated carbohydrates for site-specific glycosylation of cysteine-containing peptides and proteins via maleimide-thiol ligation reaction.
  • Synthesis of a glucuronide prodrug of doxorubicin bearing a maleimide side chain as an antitumor agent.
  • Cross-linking oligonucleotides with the amino groups on the substrate to fabricate DNA microarrays.

What are the applications of Application

6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity

Properties of N-Succinimidyl 6-maleimidohexanoate

Melting point: 70-73 °C(lit.)
Boiling point: 480.6±47.0 °C(Predicted)
Density  1.40±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  chloroform: 100mg/mL
form  powder
pka -2.21±0.20(Predicted)
color  Off-white to pale brown
Sensitive  Light & Moisture Sensitive & Hygroscopic
BRN  1499815
InChI InChI=1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
CAS DataBase Reference 55750-63-5(CAS DataBase Reference)

Safety information for N-Succinimidyl 6-maleimidohexanoate

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for N-Succinimidyl 6-maleimidohexanoate

InChIKey VLARLSIGSPVYHX-UHFFFAOYSA-N
SMILES N1(CCCCCC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O

Related products of tetrahydrofuran

You may like

  • N-Succinimidyl 6-maleimidohexanoate 98% CAS 55750-63-5
    N-Succinimidyl 6-maleimidohexanoate 98% CAS 55750-63-5
    55750-63-5
    View Details
  • N-(epsilon-Maleimidocaproyloxy) Succinimide extrapure CAS 55750-63-5
    N-(epsilon-Maleimidocaproyloxy) Succinimide extrapure CAS 55750-63-5
    55750-63-5
    View Details
  • N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent] CAS 55750-63-5
    N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent] CAS 55750-63-5
    55750-63-5
    View Details
  • N-Succinimidyl 6-maleimidohexanoate 98% (HPLC) CAS 55750-63-5
    N-Succinimidyl 6-maleimidohexanoate 98% (HPLC) CAS 55750-63-5
    55750-63-5
    View Details
  • 6-Maleimidohexanoic acid N-hydroxysuccinimide ester CAS 55750-63-5
    6-Maleimidohexanoic acid N-hydroxysuccinimide ester CAS 55750-63-5
    55750-63-5
    View Details
  • 6-Maleimidohexanoic acid N-hydroxysuccinimide ester CAS 55750-63-5
    6-Maleimidohexanoic acid N-hydroxysuccinimide ester CAS 55750-63-5
    55750-63-5
    View Details
  • 6-Maleimidohexanoic acid N-hydroxysuccinimide ester CAS 55750-63-5
    6-Maleimidohexanoic acid N-hydroxysuccinimide ester CAS 55750-63-5
    55750-63-5
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.