N-Acetyl-D-galactosamine
Synonym(s):D -GalNAc;2-Acetamido-2-deoxy-D -galactose;N-Acetylchondrosamine
- CAS NO.:14215-68-0
- Empirical Formula: C8H15NO6
- Molecular Weight: 221.21
- MDL number: MFCD00065372
- EINECS: 217-321-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-28 13:53:24
What is N-Acetyl-D-galactosamine?
Chemical properties
white to off-white fine crystalline powder
The Uses of N-Acetyl-D-galactosamine
N-Acetyl-D-galactosamine is a bio-activated reporters to visualize.
What are the applications of Application
N-Acetyl-D-galactosamine is an amino sugar derivative of galactose that is useful in forming the A blood group antigen, and is necessary for intercellular communication in nerve structures
Definition
ChEBI: N-acetyl-D-galactosamine is the D-enantiomer of N-acetylgalactosamine. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a N-acetyl-D-hexosamine and a N-acetylgalactosamine.
Enzyme inhibitor
This acetylated aminosugar (FW = 221.21 g/mol), also known as 2acetamido-2-deoxy-D-galactopyranose and abbreviated D-GalpNAc and NAGA, is a component of many glycoproteins, chondroitin, and bloodgroup substances. N-Acetyl-D-galactosamine will also inhibit the binding of ligands to many lectins. Target(s): b-N-acetylhexosaminidase; a-N-acetylgalactosaminidase; discoidins I and II, or Dictyostelium discoideum agglutinins; Bauhinia purpurea agglutinin; lima bean (Phaseolus lunatus) lectin; Wistaria floribunda phytomitogen; horse gram (Dolichos biflorus) lectin; Sophora japonica hemagglutinin; soybean (Glycine max) agglutinin; snail (Helix pomatia) hemagglutinin; a-galactosidase B; b-N-acetylglucosaminidase; b-N-acetylgalactosaminidase; galactose oxidase, also alternative substrate; keratan sulfotransferase, weakly inhibited; aralin; rRNA N-glycosylase; peptidoglycan b-N-acetylmuramidase; polypeptide N acetylgalactosaminyltransferase.
Properties of N-Acetyl-D-galactosamine
Melting point: | 158-162 °C |
Boiling point: | 362.26°C (rough estimate) |
alpha | 85 º (c=1, H2O, 5 hrs) |
Density | 1.3572 (rough estimate) |
refractive index | 85 ° (C=1, H2O) |
storage temp. | Sealed in dry,2-8°C |
solubility | Methanol (Slightly, Sonicated), Water (Slightly) |
form | Solid |
pka | 12.04±0.70(Predicted) |
color | White to Off-White |
Water Solubility | almost transparency |
Concentration | 0.1 mCi/ml |
Solvent | Ethanol:water (7:3) |
Specific Activity | 40-60 mCi/mmol |
CAS DataBase Reference | 14215-68-0(CAS DataBase Reference) |
EPA Substance Registry System | .alpha.-D-Galactopyranose, 2-(acetylamino)-2-deoxy- (14215-68-0) |
Safety information for N-Acetyl-D-galactosamine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-Acetyl-D-galactosamine
InChIKey | OVRNDRQMDRJTHS-KEWYIRBNSA-N |
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