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HomeProduct name listN-Acetyl-D-galactosamine

N-Acetyl-D-galactosamine

Synonym(s):D-GalNAc;2-Acetamido-2-deoxy-D-galactose;N-Acetylchondrosamine

  • CAS NO.:14215-68-0
  • Empirical Formula: C8H15NO6
  • Molecular Weight: 221.21
  • MDL number: MFCD00065372
  • EINECS: 217-321-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-28 13:53:24
N-Acetyl-D-galactosamine Structural

What is N-Acetyl-D-galactosamine?

Chemical properties

white to off-white fine crystalline powder

The Uses of N-Acetyl-D-galactosamine

N-Acetyl-D-galactosamine is a bio-activated reporters to visualize.

What are the applications of Application

N-Acetyl-D-galactosamine is an amino sugar derivative of galactose that is useful in forming the A blood group antigen, and is necessary for intercellular communication in nerve structures

Definition

ChEBI: N-acetyl-D-galactosamine is the D-enantiomer of N-acetylgalactosamine. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a N-acetyl-D-hexosamine and a N-acetylgalactosamine.

Enzyme inhibitor

This acetylated aminosugar (FW = 221.21 g/mol), also known as 2acetamido-2-deoxy-D-galactopyranose and abbreviated D-GalpNAc and NAGA, is a component of many glycoproteins, chondroitin, and bloodgroup substances. N-Acetyl-D-galactosamine will also inhibit the binding of ligands to many lectins. Target(s): b-N-acetylhexosaminidase; a-N-acetylgalactosaminidase; discoidins I and II, or Dictyostelium discoideum agglutinins; Bauhinia purpurea agglutinin; lima bean (Phaseolus lunatus) lectin; Wistaria floribunda phytomitogen; horse gram (Dolichos biflorus) lectin; Sophora japonica hemagglutinin; soybean (Glycine max) agglutinin; snail (Helix pomatia) hemagglutinin; a-galactosidase B; b-N-acetylglucosaminidase; b-N-acetylgalactosaminidase; galactose oxidase, also alternative substrate; keratan sulfotransferase, weakly inhibited; aralin; rRNA N-glycosylase; peptidoglycan b-N-acetylmuramidase; polypeptide N acetylgalactosaminyltransferase.

Properties of N-Acetyl-D-galactosamine

Melting point: 158-162 °C
Boiling point: 362.26°C (rough estimate)
alpha  85 º (c=1, H2O, 5 hrs)
Density  1.3572 (rough estimate)
refractive index  85 ° (C=1, H2O)
storage temp.  Sealed in dry,2-8°C
solubility  Methanol (Slightly, Sonicated), Water (Slightly)
form  Solid
pka 12.04±0.70(Predicted)
color  White to Off-White
Water Solubility  almost transparency
Concentration 0.1 mCi/ml
Solvent Ethanol:water (7:3)
Specific Activity 40-60 mCi/mmol
CAS DataBase Reference 14215-68-0(CAS DataBase Reference)
EPA Substance Registry System .alpha.-D-Galactopyranose, 2-(acetylamino)-2-deoxy- (14215-68-0)

Safety information for N-Acetyl-D-galactosamine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for N-Acetyl-D-galactosamine

InChIKey OVRNDRQMDRJTHS-KEWYIRBNSA-N

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