Ethyl 3-(pyridin-2-ylamino)propanoate
- CAS NO.:103041-38-9
- Empirical Formula: C10H14N2O2
- Molecular Weight: 194.23
- MDL number: MFCD09833621
- EINECS: 600-382-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-21 22:41:43
What is Ethyl 3-(pyridin-2-ylamino)propanoate?
Chemical properties
White Solid
The Uses of Ethyl 3-(pyridin-2-ylamino)propanoate
Ethyl 3-(2-Pyridylamino)propanoate is an intermediate used in the synthesis of Dabigatran etexilate, as thrombin inhibitors. Ethyl Ester form of P993315.
Synthesis
A method for preparing Ethyl 3-(pyridin-2-ylamino)propanoate comprises the following steps: using 2-aminopyridine and ethyl acrylate as raw materials, using anhydrous ethanol as a solvent, using trifluoromethanesulfonic acid as a catalyst, and heating in an oil bath to control the temperature at 120 to 160° C. for a catalytic reaction for 16 to 20 hours under nitrogen protection. The obtained reaction solution is washed with petroleum ether at a temperature of 35 to 40° C. and a pressure of 0.09 to 0.1 MPa, then concentrated under reduced pressure, and then washed with petroleum ether/ethyl acetate and recrystallized to obtain white flaky crystals of Ethyl 3-(pyridin-2-ylamino)propanoate.
Properties of Ethyl 3-(pyridin-2-ylamino)propanoate
Melting point: | 48-50°C |
Boiling point: | 125°C/0.2mmHg(lit.) |
Density | 1.131±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | DMSO, Methanol |
form | Solid |
pka | 6.26±0.10(Predicted) |
color | White |
InChI | InChI=1S/C10H14N2O2/c1-2-14-10(13)6-8-12-9-5-3-4-7-11-9/h3-5,7H,2,6,8H2,1H3,(H,11,12) |
Safety information for Ethyl 3-(pyridin-2-ylamino)propanoate
Computed Descriptors for Ethyl 3-(pyridin-2-ylamino)propanoate
InChIKey | UITNIDFEANEWPC-UHFFFAOYSA-N |
SMILES | C(OCC)(=O)CCNC1C=CC=CN=1 |
Abamectin manufacturer
SYNGREEN LIFESCIENCES PVT.LTD
Neochemsys Laboratories Pvt Ltd
Greenovel life sciences Pvt Ltd
KARPSCHEM LABORATORIES PVT. LTD.
JSK Chemicals
SVK Laboratories Pvt Ltd
Vepan Pharmatech Pvt Ltd
Viyash Life Sciences Pvt Ltd
New Products
Bromine 99.5% AR (4 x 500ml) Fehling's Solution No. B Amino Acid Kit of 23 items set Ammonium Molybdate Reagent Solution Beam's Reagent Solution Ehrlich's Reagent For detection of urobillinogen Sodium Amino Salicylate Dihydrate (PAS Sodium) IP/BP/USP/EP 1,2,3,4-Tetrahydrocarbazol-4-one 4-Hydroxy Carbazole Amino Salicylic Acid. U.S.P. 2 – Methoxy – 5- Sulfamoyl Benzoic acid Acetone Isobutryl oxime ester Curcuma aromatica Oil Curry leaf Extract Terminalia bellirica Extract Aloe vera extract 200x Withania somnifera (Ashwagandha Extract) Citrus bioflavonoids Extract Ethyl 3-(Pyridin-2-Ylamino)Propanoate Bilastine -IP/BP/ Cypermethric Acid Chloride 5-Nitrosalicylaldehyde 5-(Difluoromethoxy)-2-Mercapto-1H-Benzimidazole- IP/BP/ Methyl Di Chloride (Mdc)Related products of tetrahydrofuran
You may like
-
103041-38-9 ethyl 3-(pyridin-2-ylamino)propanoate 98%View Details
103041-38-9 -
Ethyl 3-(2-Pyridylamino) Propionate 103041-38-9 99%View Details
103041-38-9 -
Ethyl 3-(2-Pyridylamino)propionate CAS 103041-38-9View Details
103041-38-9 -
Ethyl 3-(Pyridin-2-ylamino)-propionoate 98%View Details
-
Ethyl 3-(Pyridin-2-ylamino)-propionoate 98%View Details
-
Ethyl 3-(Pyridin-2-ylamino)-propionoate 98%View Details
-
N-2-Pyridinyl-beta-alanine ethyl ester 99% (GC) CAS 103041-38-9View Details
103041-38-9 -
Ethyl 3-(pyridin-2-ylamino)propanoate CAS 103041-38-9View Details
103041-38-9