3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester

CAS NO.：211915-84-3
Empirical Formula: C27H26N6O3
Molecular Weight: 482.53
MDL number: MFCD09833627
EINECS: 1592732-453-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-09-07 14:58:50

What is 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester?

Description

3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester is a pharmaceutical intermediate compound. It can be used to prepare Dabigatran etexilate.The drug is used to reduce the risk of stroke and blood clots in patients with a serious heart rhythm problem called non-valvular atrial fibrillation.

Chemical properties

White Solid

The Uses of 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester

Nonpeptide thrombin inhibitor intermediate.

Properties of 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester

Melting point:	149-151°C
Boiling point:	756.4±60.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly, Sonicated), Methanol (Very Slightly, Sonicated)
form	Solid
pka	4.21±0.10(Predicted)
color	White to Pale Beige

Safety information for 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P330:Rinse mouth. P362:Take off contaminated clothing and wash before reuse. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…

Computed Descriptors for 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester

InChIKey	OZBOESGNDSVMDK-UHFFFAOYSA-N
SMILES	C(OCC)(=O)CCN(C(C1=CC=C2N(C)C(CNC3=CC=C(C#N)C=C3)=NC2=C1)=O)C1=NC=CC=C1

3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester manufacturer

GRK RESEARCH LABORATORIES PVT LTD

Phone:+91-7093001765

Whatsapp: +91- 7093001765

product: 211915-84-3 5-benzoyl-2,3- dibromo-1-(1,1-dicarbomethoxy)-3-propyl pyrrole 98%+

Inquiry

Deepa Pharma

Mumbai

Phone:91-9821962248

Whatsapp: 91-9821962248

product: Ethyl 3-({2-[(4-cyano-phenylamino)methyl]-1-methyl-1H-benzoimidazole-5-carbonyl}pyridin-2-ylamino)propionate

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