Mutant IDH1 inhibitor
- CAS NO.：1429180-08-4
- Empirical Formula: C25H34N6O3
- Molecular Weight: 466.58
- Update Date: 2024-11-19 23:02:33
What is Mutant IDH1 inhibitor?
Description
Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM.
in vitro
In Vitro:Mutant IDH1 inhibitor is a potent IDH1 R132H inhibitor, and used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer[1].
References
References:[1]. 3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation. Patent WO 2013046136 A1 20130404
Properties of Mutant IDH1 inhibitor
| storage temp. | Store at -20°C |
| solubility | DMSO: ≥ 34 mg/mL (72.87 mM) |
| form | Powder |
| color | White to light yellow |
Safety information for Mutant IDH1 inhibitor
Computed Descriptors for Mutant IDH1 inhibitor
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