MUSCIMOL HYDRATE
- CAS NO.：18174-72-6
- Empirical Formula: C4H6N2O2.BrH
- Molecular Weight: 195.01
- MDL number: MFCD00150633
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is MUSCIMOL HYDRATE?
Description
Muscimol HBr (18174-72-6) is a GABA-A receptor agonist.
Chemical properties
Tan Solid
The Uses of MUSCIMOL HYDRATE
A potent but toxic structural analogue of g-aminobutyric acid (GABA), with a zwitterionic structure that can cross the blood-brain barrier.
What are the applications of Application
Muscimol hydrobromide is a potent but toxic structural analog of g-aminobutyric acid (GABA)
Biochem/physiol Actions
Muscimol hydrobromide is a GABAA receptor agonist.
References
1) Akhondzadeh et al. (1995), Induction of a novel form of hippocampal long-term depression by muscimol: involvement of GABAA but not glutamate receptors; Br. J. Pharmacol., 115 527
Properties of MUSCIMOL HYDRATE
| Melting point: | 172 °C |
| storage temp. | 2-8°C |
| solubility | ethanol: 1 mg/mL |
| form | powder |
| color | off-white |
| Stability: | Store in freezer at -20°C |
| InChI | InChI=1S/C4H6N2O2.BrH/c5-2-3-1-4(7)6-8-3;/h1H,2,5H2,(H,6,7);1H |
Safety information for MUSCIMOL HYDRATE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for MUSCIMOL HYDRATE
| InChIKey | OPZOJWHOZRKYQX-UHFFFAOYSA-N |
| SMILES | C1(CN)ON=C(O)C=1.Br |
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![MUSCIMOL, [METHYLENE-3H(N)]](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB1735998.gif)
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