Mometasone

CAS NO.：105102-22-5
Empirical Formula: C22H28Cl2O4
Molecular Weight: 427.36
MDL number: MFCD02683426
EINECS: 818-819-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-09-19 17:15:21

What is Mometasone?

Chemical properties

Pale Yellow Solid

The Uses of Mometasone

Mometasone is a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders.

The Uses of Mometasone

Mometasone (Mometasone EP Impurity G) is a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders. It can be applied to the skin, inhaled, or used in the nose. It is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis. Mometasone furoate, not mometasone, is used in medical products.

Definition

ChEBI: Mometasone is an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a chlorinated steroid and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug, a dermatologic drug, a vasoconstrictor agent and an anti-allergic agent. It is functionally related to a Delta(1)-progesterone.

Side Effects

The most common side effects are an unpleasant smell and a dry or sore nose or throat.

Properties of Mometasone

Melting point:	>211oC (dec.)
Boiling point:	586.6±50.0 °C(Predicted)
Density	1.35±0.1 g/cm3(Predicted)
storage temp.	Refrigerator, Under Inert Atmosphere
solubility	DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form	Solid
pka	12.08±0.70(Predicted)
color	White to Pale Beige
CAS DataBase Reference	105102-22-5(CAS DataBase Reference)

Safety information for Mometasone

Computed Descriptors for Mometasone

InChIKey	WOFMFGQZHJDGCX-MCUOXHNDNA-N
SMILES	[C@]1(OC(=O)C2OC=CC=2)([C@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C)C(CCl)=O \|&1:0,9,12,14,24,26,28,31,r\|