ML-9 HYDROCHLORIDE
Synonym(s):1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride;1-(5-Chloronaphthalene-1-sulfonyl)homopiperazine, HCl;ML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem
- CAS NO.：105637-50-1
- Empirical Formula: C15H18Cl2N2O2S
- Molecular Weight: 361.28
- MDL number: MFCD00065525
- EINECS: 200-258-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-18 17:01:59
What is ML-9 HYDROCHLORIDE?
Chemical properties
Crystalline Solid
The Uses of ML-9 HYDROCHLORIDE
Inhibits the catalytic activities of several protein kinases competitively with respect to ATP and exhibited different Ki values toward each protein kinase. Also found to be a new type of vascular relaxant
The Uses of ML-9 HYDROCHLORIDE
Inhibits the catalytic activities of several protein kinases competitively with respect to ATP and exhibited different Ki values toward each protein kinase. Also found to be a new type of vascular relaxant.
What are the applications of Application
ML-9 is a selective inhibitor of MYLK, CaMK, PKB Kinase, PKA, and Stim1
Biological Activity
Selective inhibitor of myosin light chain kinase (MLCK). K i values are 32, 4, and 54 μ M for PKA, MLCK, and PKC respectively. Also inhibits STIM1-plasma membrane interactions, preventing store-operated Ca 2+ entry (SOCE).
storage
Desiccate at RT
Properties of ML-9 HYDROCHLORIDE
| Melting point: | 196-200 |
| storage temp. | 2-8°C |
| solubility | ethanol: 10 mg/mL |
| form | powder |
| color | white |
Safety information for ML-9 HYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for ML-9 HYDROCHLORIDE
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-(2,4-Dimethoxybenzyl)dihydropyrimidine-2,4(1H,3H)-dione 7-Bromo-1H-indazole N-octanoyl benzotriazole 3,4-Dibenzyloxybenzaldehyde 4-Hydrazinobenzoic acid Electrolytic Iron Powder Fmoc-Val-Cit-PAB 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 4-HYDROXY BENZYL ALCOHOL 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) S-2-CHLORO PROPIONIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 1-(4-Methylphenylsulfonyl)-1H-1,2,3-benzotriazole 1-(2-Chlorobenzyl)-4-nitro-1H-pyrazole 1-(2-Nitrophenyl)-4-phenylpiperazineRelated products of tetrahydrofuran
You may like
-
55441-95-7 2 2-BIS(2-HYDROXYETHOXY)-1 1-BINAPHTHYL 99%View Details
55441-95-7 -
181228-33-1 99%View Details
181228-33-1 -
Ste-Glu-AEEA-AEEA-OSUView Details
1169630-40-3 -
1446013-08-6 Fmoc-His-Aib-OH TFA 98%View Details
1446013-08-6 -
127464-43-1 99%View Details
127464-43-1 -
Chloro Uracil 99%View Details
1820-81-1 -
2-ETHYLPYRIDINE 100-71-0 99%View Details
100-71-0 -
13162-05-5 99%View Details
13162-05-5
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.