MK-2048
- CAS NO.:869901-69-9
- Empirical Formula: C21H21ClFN5O4
- Molecular Weight: 461.87
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:08
What is MK-2048?
The Uses of MK-2048
MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir (R100312). MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir.
The Uses of MK-2048
MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir (R100312). MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir.
What are the applications of Application
MK-2048 is a second generation integrase inhibitor for HIV-1 integrase and INR263K
Properties of MK-2048
Density | 1.55 |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO > 10 mM |
form | Powder |
pka | 6.30±0.40(Predicted) |
color | Light yellow to yellow |
Safety information for MK-2048
Computed Descriptors for MK-2048
New Products
Tubulysin A 2,2-diethoxyethanethioamide (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin F 2H-Pyran, 4-ethynyltetrahydro- 3-N-BOC-(S)-AMINO BUTYRONITRILE 4,4-DIFLUOROCYCLOHEXANAMINE 4-(Benzyloxy)-3-bromophenylacetic Acid 3-FLUOROPYRROLIDINE HYDROCHLORIDE 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell Calcium Sodium Phosphosilicate IH 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 5-Piperazin-1-yl- benzofuran-2- carboxylic acid ethyl ester. HCl (S)-3-(3-fluoro- 4-thiomorpholinophenyl) -4-(hydroxymethyl) oxazolidin-2-one Magnesium Trisilicate Lubiprostone Latanoprostene Bunod Flame Retardant Zinc Borate 7-Methoxyquinoline-4-carboxylic acid 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
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