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HomeProduct name listMK-2048

MK-2048

MK-2048 Structural

What is MK-2048?

The Uses of MK-2048

MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir (R100312). MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir.

The Uses of MK-2048

MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir (R100312). MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir.

What are the applications of Application

MK-2048 is a second generation integrase inhibitor for HIV-1 integrase and INR263K

Properties of MK-2048

Density  1.55
storage temp.  Store at -20°C
solubility  Soluble in DMSO > 10 mM
form  Powder
pka 6.30±0.40(Predicted)
color  Light yellow to yellow

Safety information for MK-2048

Computed Descriptors for MK-2048

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