Dibenzyl phosphite

Synonym(s):Dibenzyl phosphonate

CAS NO.：17176-77-1
Empirical Formula: C14H15O3P
Molecular Weight: 262.24
MDL number: MFCD00004774
EINECS: 241-226-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is Dibenzyl phosphite?

Chemical properties

Clear colorless to yellow liquid

The Uses of Dibenzyl phosphite

Dibenzyl Phosphite is used in the preparation of phenylalkylphosphonamidates which are then used as probes for a hydrophobic binding register in prostate-specific membrane antigen.

The Uses of Dibenzyl phosphite

In preparation of N-phosphorylated amines.

The Uses of Dibenzyl phosphite

Dibenzyl phosphite is used for the phosphorylation of phenols involves reaction in the presence of N-ethyldiisopropylamine and DMAP to give the dibenzyl phenyl phosphate. It is used in the preparation of phenylalkylphosphonamidates which are then used as probes for a hydrophobic binding register in prostate-specific membrane antigen.

Properties of Dibenzyl phosphite

Melting point:	0 to 5°
Boiling point:	110-120 °C/0.01 mmHg (lit.)
Density	1.187 g/mL at 25 °C (lit.)
refractive index	n20/D 1.555(lit.)
Flash point:	>230 °F
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Liquid
color	Clear colorless to yellow
Water Solubility	Soluble in DMSO, Methanol. Reacts with water.
Sensitive	Air & Moisture Sensitive
Merck	14,3014
BRN	1982794
CAS DataBase Reference	17176-77-1(CAS DataBase Reference)
NIST Chemistry Reference	Dibenzyl phosphite(17176-77-1)

Safety information for Dibenzyl phosphite

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.