Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate
- CAS NO.：42245-42-1
- Empirical Formula: C11H12O4
- Molecular Weight: 208.21
- MDL number: MFCD00012316
- EINECS: 255-735-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate?
Description
Methyl 2,3 epoXY-3-(4-methoxyphenyl)propionate is an intermediate product in the synthesis of diltiazem hydrochloride. Contact dermatitis was observed in several laboratory technicians.
The Uses of Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate
Methyl trans-3-(4-Methoxyphenyl)glycidate is an intermediate used in the synthesis of Clentiazem (C573035), which is a benzothiazepine-like calcium antagonists; Enhances endothelium-dependent coronary artery relaxation.
Contact allergens
Methyl 2,3 epoxy-3-(4-methoxyphenyl)propionate is an intermediate product in the synthesis of diltiazem hydrochloride. Contact dermatitis was observed in several laboratory technicians.
Properties of Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate
| Melting point: | 69-71 °C(lit.) |
| solubility | Dichloromethane; Chloroform; Ethyl Acetate; DMSO; |
| form | Solid |
| color | White |
| EPA Substance Registry System | Oxiranecarboxylic acid, 3-(4-methoxyphenyl)-, methyl ester (42245-42-1) |
Safety information for Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate
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