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HomeProduct name listMesulfen

Mesulfen

  • CAS NO.:135-58-0
  • Empirical Formula: C14H12S2
  • Molecular Weight: 244.38
  • MDL number: MFCD00046937
  • EINECS: 205-202-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-06 17:15:42
Mesulfen Structural

What is Mesulfen?

Originator

Mesulfen ,Synopharm GMBH and CO.KG

The Uses of Mesulfen

Mesulfen has been used in the study of therapy of seborrhea, seborrheic eczema and acne in a soap base.

The Uses of Mesulfen

A mixture of dimethylthianthrene and ditoluene- disulfide.

Definition

ChEBI: Mesulfen is a thianthrene.

Manufacturing Process

100 parts by weight of toluene, 330 parts of sulfur and 80 parts of aluminum chloride were heated to reflux on the oil bath before the formation of hydrogen sulfide and hydrogen chloride ended. The mixture was poured into water for removing the excess of aluminum chloride. A toluene layer was separated, dried and distilled in vacuum. When toluene was distilled off, about 500 parts by weight the residual yellow oil boiled at 150°-230°C/3 mm Hg was yielded. An objectionable odor was removed by shaking with sodium hydroxide. The residual sulfur (23-25%) was removed by washing with hydrogen peroxide. The residue (mesulfen) looked like fragile asphalt mass after distillation.

Therapeutic Function

Scabicide

Properties of Mesulfen

Melting point: 123°
Boiling point: bp3 184°; bp14 228-231°
Density  1.2773 (rough estimate)
refractive index  1.6210 (estimate)
CAS DataBase Reference 135-58-0(CAS DataBase Reference)

Safety information for Mesulfen

Computed Descriptors for Mesulfen

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