Mesulfen
- CAS NO.:135-58-0
- Empirical Formula: C14H12S2
- Molecular Weight: 244.38
- MDL number: MFCD00046937
- EINECS: 205-202-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-06 17:15:42
What is Mesulfen?
Originator
Mesulfen ,Synopharm GMBH and CO.KG
The Uses of Mesulfen
Mesulfen has been used in the study of therapy of seborrhea, seborrheic eczema and acne in a soap base.
The Uses of Mesulfen
A mixture of dimethylthianthrene and ditoluene- disulfide.
Definition
ChEBI: Mesulfen is a thianthrene.
Manufacturing Process
100 parts by weight of toluene, 330 parts of sulfur and 80 parts of aluminum chloride were heated to reflux on the oil bath before the formation of hydrogen sulfide and hydrogen chloride ended. The mixture was poured into water for removing the excess of aluminum chloride. A toluene layer was separated, dried and distilled in vacuum. When toluene was distilled off, about 500 parts by weight the residual yellow oil boiled at 150°-230°C/3 mm Hg was yielded. An objectionable odor was removed by shaking with sodium hydroxide. The residual sulfur (23-25%) was removed by washing with hydrogen peroxide. The residue (mesulfen) looked like fragile asphalt mass after distillation.
Therapeutic Function
Scabicide
Properties of Mesulfen
Melting point: | 123° |
Boiling point: | bp3 184°; bp14 228-231° |
Density | 1.2773 (rough estimate) |
refractive index | 1.6210 (estimate) |
CAS DataBase Reference | 135-58-0(CAS DataBase Reference) |
Safety information for Mesulfen
Computed Descriptors for Mesulfen
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