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HomeProduct name listMestanolone

Mestanolone

Synonym(s):Mestanolone;Methylandrostanolone;Mestaline;17α-Methyldihydrotestosterone;17β-Hydroxy-17α-methyl-5α-androstan-3-one

  • CAS NO.:521-11-9
  • Empirical Formula: C20H32O2
  • Molecular Weight: 304.47
  • MDL number: MFCD00021158
  • EINECS: 208-302-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-28 19:50:54
Mestanolone Structural

What is Mestanolone?

Description

Mestanolone is an orally active anabolic-androgenic steroid and the 17α-methylated derivative of dihydrotestosterone (DHT), which is an endogenous androgen sex steroid and hormone. It is capable of increasing testosterone benefit, suppressing estrogen effect, leaning muscle tissue, increasing strength as well as improving drive and focus. It is mainly used for the treatment of male hypogonadism and decreased sperm infertility.

Chemical properties

White Solid

The Uses of Mestanolone

Anabolic steroid. Controlled substance.

Definition

ChEBI: Mestanolone is a 3-oxo-5alpha-steroid.

Purification Methods

Dissolve mestanolone in Et2O, wash it with N NaOH, H2O, dry it (Na2SO4), evaporate and recrystallise it from EtOAc. The semicarbazone has m 235-236o (from EtOH). [Ruzicka et al. Helv Chim Acta 18 1487 1935.]

References

https://en.wikipedia.org/wiki/Mestanolone
https://en.wikipedia.org/wiki/Dihydrotestosterone#Medical_use
http://www.biopharmchem.com/raw-hormone-ermalone-oral-steroid-mestanolone-p01138p1.html

Properties of Mestanolone

Melting point: 191 °C
Boiling point: 385.28°C (rough estimate)
Density  1.0279 (rough estimate)
refractive index  1.4824 (estimate)
storage temp.  Controlled Substance, -20°C Freezer
solubility  Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
pka 15.15±0.60(Predicted)
form  neat
Merck  5915
InChI InChI=1/C20H32O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h13,15-17,22H,4-12H2,1-3H3/t13-,15+,16-,17-,18-,19-,20-/s3
CAS DataBase Reference 521-11-9(CAS DataBase Reference)
NIST Chemistry Reference Mestanolone(521-11-9)

Safety information for Mestanolone

Signal word Danger
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H351:Carcinogenicity
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P202:Do not handle until all safety precautions have been read and understood.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P273:Avoid release to the environment.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for Mestanolone

InChIKey WYZDXEKUWRCKOB-YDSAWKJFSA-N
SMILES C[C@]12CCC(=O)C[C@]1([H])CC[C@@]1([H])[C@]3([H])CC[C@@](O)(C)[C@@]3(C)CC[C@]21[H] |&1:1,7,11,13,17,20,24,r|

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