Mercaptosuccinic acid

Synonym(s):Mercaptosuccinic acid;Thiomalic acid

CAS NO.：70-49-5
Empirical Formula: C4H6O4S
Molecular Weight: 150.15
MDL number: MFCD00004860
EINECS: 200-736-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is Mercaptosuccinic acid?

Chemical properties

white to almost white crystalline powder

The Uses of Mercaptosuccinic acid

Mercaptosuccinic acid is used in the preparation of mercaptosuccinic acid diethyl ester by reaction with ethanol. It is also used as a brightening agent in metal plating. Further, it serves as an intermediate for the synthesis of corrosion inhibitors, soil fumigants, active pharmaceutical ingredients and electroplating agents.

The Uses of Mercaptosuccinic acid

Antirheumatic.

The Uses of Mercaptosuccinic acid

Mercaptosuccinic acid has been used as a dopant for the synthesis of carbon nanodots from citric acid. It can be used as a capping and reducing agent to synthesize monolayer-capped gold nanoparticles.

Definition

ChEBI: Thiomalic acid is a C4-dicarboxylic acid. It is functionally related to a succinic acid. It is a conjugate acid of a thiomalate(1-).

brand name

Myochrysine (Merck).

General Description

Mercaptosuccinic acid(MSA) is a chiral multifunctional intermediate material used as a stabilizing and capping agent in the synthesis of biologically active sulfurs.

Purification Methods

Dissolve the acid in water and extract it several times with diethyl ether to remove imprities. The aqueous solution gave the acid on freeze-drying. [Beilstein 3 IV 472.]

Properties of Mercaptosuccinic acid

Melting point:	155-157 °C(lit.)
Boiling point:	241.69°C (rough estimate)
Density	1.352 (estimate)
refractive index	1.5500 (estimate)
storage temp.	Store below +30°C.
solubility	500g/l
pka	pKa 4.68±0.04(H2O t = 20.0±0.05 I = 0.15) (Uncertain)
form	Crystalline Powder
color	White to almost white
Water Solubility	150 g/L (20 ºC)
Merck	14,9343
BRN	1099858
CAS DataBase Reference	70-49-5(CAS DataBase Reference)
NIST Chemistry Reference	2-Sulfanylsuccinic acid(70-49-5)
EPA Substance Registry System	Butanedioic acid, mercapto- (70-49-5)

Safety information for Mercaptosuccinic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.