Mepacrine hydrochloride

CAS NO.：6151-30-0
Empirical Formula: C23H36Cl3N3O3
Molecular Weight: 508.91
MDL number: MFCD00150069
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-21 10:59:17

What is Mepacrine hydrochloride?

Chemical properties

bright yellow powder

The Uses of Mepacrine hydrochloride

Quinacrine Dihydrochloride Dihydrate is a phophoslipase A2 inhibitor.

What are the applications of Application

Quinacrine Dihydrochloride Dihydrate is a phophoslipase A2 inhibitor

General Description

Qunacrine is no longer available in theUnited States. It can be considered one of the most toxic ofthe antimalarial drugs even though, at one time, it was commonlyused. It acts at many sites within the cell includingintercalation of DNA strands, succinic dehydrogenase andmitochondrial electron transport, and cholinesterase. It maybe tumorgenic and mutagenic and has been used as a sclerosingagent. Because it is an acridine dye, quinacrine cancause yellow discoloration of the skin and urine.

Properties of Mepacrine hydrochloride

Melting point:	247 °C
storage temp.	Store at -20°C
solubility	DMSO: 10 mg/mL (19.65 mM);;
Water Solubility	2.8 g/100 mL
CAS DataBase Reference	6151-30-0(CAS DataBase Reference)

Safety information for Mepacrine hydrochloride

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.