Menthyl anthranilate

Synonym(s):Menthyl o-aminobenzoate;Menthyl anthranilate

CAS NO.：134-09-8
Empirical Formula: C17H25NO2
Molecular Weight: 275.39
MDL number: MFCD00045487
EINECS: 205-129-8
SAFETY DATA SHEET (SDS)
Update Date: 2023-11-23 20:02:38

What is Menthyl anthranilate?

Absorption

Meradimate is not absorbed through the skin.

Toxicity

Meradimate is considered safe but some studies have shown that it can increase the production of reactive oxygen species.

The Uses of Menthyl anthranilate

menthyl anthranilate is the only FDA-approved liquid sunscreen chemical with uVA-absorption capabilities. It has an approved usage level of 3.5 to 5 percent. This is a stable ingredient and can be combined with other sunscreen chemicals to increase SPF while providing uVA protection.

The Uses of Menthyl anthranilate

Meradimate or menthyl anthranilate is a weak UVB filter and with absorption mainly in the near UVA portion of the spectrum. They are less effective than benzophenones in this range and are less widely used.

The Uses of Menthyl anthranilate

Menthyl Anthranilate is used as a UV filter in skin care formulations.

Indications

Meradimate is used as an active ingredient in sunscreens or as a sunblock factor in different products. It fits under the category of broad-spectrum absorbent agent. These characteristics are important to consider due to the fact that this kind of ingredients can either absorb or reflect UV radiation. It is also important to know the type of rays that cover. UVA rays are the responsible of causing sun damage and reaching deeper layers of the skin while UVB can only cause sunburn in the outer layer of the skin. When an agent is of broad spectrum, this means that this agent is capable of acting in both UVA and UVB rays.

Background

Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products.

Definition

ChEBI: Meradimate is a monoterpenoid.

General Description

Menthyl anthranilate is a fluorescent agent and a UV filter that can be used as an alternative to oxybenzone. It is majorly used in sunscreen based products. It can be easily mixed in cosmetic oils and can also be emulsified in aqueous formulations.

Pharmacokinetics

Meradimate effect provides a low-level, broad-spectrum protecting coverage effect.

Metabolism

As meradimate is not absorbed, this pharmacokinetic property is not relevant.

Properties of Menthyl anthranilate

Melting point:	62.5-63.5°
Boiling point:	177-179 °C3 mm Hg(lit.)
Density	1.04 g/mL at 25 °C(lit.)
refractive index	n20/D 1.542(lit.)
Flash point:	>230 °F
pka	2.17±0.10(Predicted)
Odor	at 100.00 %. grape menthol
EPA Substance Registry System	Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 2-aminobenzoate (134-09-8)

Safety information for Menthyl anthranilate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.