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HomeProduct name listMelagatran

Melagatran

Melagatran Structural

What is Melagatran?

Chemical properties

White Solid

The Uses of Melagatran

Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic

The Uses of Melagatran

Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic.

What are the applications of Application

Melagatran is A thrombin mutant anticoagulant antagonist.

Definition

ChEBI: Melagatran is a member of the class of azetidines that is (2S)-azetidine 2-carboxylic acid in which the carboxylic acid has been converted to the amide corresponding to formal condensation with 4-(aminomethyl)benzenecarboximidamide and in which the hydrogen attached to the azetidine nitrogen is replaced by a (2R)-2-cyclohexyl-2-[(carboxymethyl)amino]acetyl group. It has a role as an anticoagulant, an EC 3.4.21.5 (thrombin) inhibitor and a serine protease inhibitor. It is a carboxamidine, a dicarboxylic acid monoamide, a non-proteinogenic alpha-amino acid, a secondary amino compound and a member of azetidines.

Properties of Melagatran

Melting point: 198-200°C
Density  1.41±0.1 g/cm3(Predicted)
storage temp.  Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 2.12±0.10(Predicted)
color  White to Off-White
Stability: Hygroscopic

Safety information for Melagatran

Computed Descriptors for Melagatran

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