Mal-PEG2-NHS ester
- CAS NO.：1433997-01-3
- Empirical Formula: C15H18N2O8
- Molecular Weight: 354.31
- MDL number: MFCD24539465
- Update Date: 2024-03-27 14:23:05
What is Mal-PEG2-NHS ester?
Description
Mal-PEG2-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
The Uses of Mal-PEG2-NHS ester
Mal-?PEG2-?NHS Ester is a reagent used in the preparation of antibody-drug conjugates that bind to human-antigen targets in the effort to combat cancers.
Properties of Mal-PEG2-NHS ester
| Boiling point: | 524.3±60.0 °C(Predicted) |
| Density | 1.42±0.1 g/cm3(Predicted) |
| solubility | Soluble in DCM |
| pka | -2.34±0.20(Predicted) |
| form | Oil |
| color | Colourless |
Safety information for Mal-PEG2-NHS ester
Computed Descriptors for Mal-PEG2-NHS ester
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