Mal-Amido-PEG4-acid
- CAS NO.：1263045-16-4
- Empirical Formula: C18H28N2O9
- Molecular Weight: 416.42
- MDL number: MFCD13184954
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is Mal-Amido-PEG4-acid?
Description
Mal-amido-PEG4-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Properties of Mal-Amido-PEG4-acid
| Boiling point: | 659.1±55.0 °C(Predicted) |
| Density | 1.270±0.06 g/cm3(Predicted) |
| solubility | Soluble in Water, DMSO, DMF, DCM |
| pka | 4.28±0.10(Predicted) |
| form | powder to crystal |
| color | White to Gray to Brown |
| CAS DataBase Reference | 1263045-16-4 |
Safety information for Mal-Amido-PEG4-acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Mal-Amido-PEG4-acid
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