LY-2608204
- CAS NO.：1234703-40-2
- Empirical Formula: C28H37N3O3S3
- Molecular Weight: 559.81
- MDL number: MFCD21609257
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-14 14:09:35
What is LY-2608204?
Description
LY2608204 is an activator of glucokinase (GK; EC50 = 42 nM). It stimulates glucose metabolism in INS-1E rat insulinoma cells (mean EC50 = 579 nM). LY2608204 (30 mg/kg) decreases plasma glucose levels in a dose-dependent manner in fasted rats.
References
[1] kj filipski, bd stevens . glucokinase activators in development .2012 books
Properties of LY-2608204
| Density | 1.35 |
| storage temp. | Store at -20°C |
| solubility | ≥28.35 mg/mL in DMSO; insoluble in H2O; ≥26.2 mg/mL in EtOH |
| form | solid |
| pka | 8.17±0.70(Predicted) |
| color | White to off-white |
Safety information for LY-2608204
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for LY-2608204
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Diclofenac Potassium Ornidazole IP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Aceclofenac IP/BP/EP Nimesulide BP SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION AMOXICILLIN (AMOXYCILLIN) TRIHYDRATE Methylcobalamin (vitamin B12) SODIUM VALPROATE SODIUM METHYL PARABEN LAMOTRIGINERelated products of tetrahydrofuran
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