Lurasidone hydrochloride

CAS NO.：367514-88-3
Empirical Formula: C28H37ClN4O2S
Molecular Weight: 529.14
MDL number: MFCD18917095
EINECS: 682-423-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-01 14:32:37

What is Lurasidone hydrochloride?

Chemical properties

Off-White Solid

The Uses of Lurasidone hydrochloride

An antipsychotic used for treatment of schizophrenia.

The Uses of Lurasidone hydrochloride

Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively

Definition

ChEBI: A hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. An atypical antipsychotic agent used for the treatment of schizophrenia.

Properties of Lurasidone hydrochloride

Melting point:	198-205°C
Flash point:	9℃
storage temp.	Refrigerator
solubility	DMSO : 10 mg/mL (18.90 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form	Powder
color	White to off-white

Safety information for Lurasidone hydrochloride

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H225:Flammable liquids H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for Lurasidone hydrochloride

InChIKey	PQXKDMSYBGKCJA-CVTJIBDQSA-N
SMILES	O=C1N(C(=O)[C@@]2([H])[C@]3([H])CC[C@@]([H])(C3)[C@@]12[H])C[C@@H]1CCCC[C@H]1CN1CCN(C2=NSC3=CC=CC=C23)CC1.Cl \|&1:5,7,11,14,17,22,r\|