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HomeProduct name listLL-37

LL-37

  • CAS NO.:154947-66-7
  • Empirical Formula: C205H340N60O53
  • Molecular Weight: 0
  • MDL number: MFCD09264694
  • EINECS: 211-519-9
  • Update Date: 2024-10-30 18:52:02

What is LL-37?

Origin

Mammalian AMPs belong to the defensin and cathelicidin families. So far, there is a unique cathelicidin peptide found in 1995 and called human cationic antimicrobial peptide (hCAP18). Its active part starts with double leucine and consists of 37-amino acids at the C-terminus, so which is called LL-37.

Benefits

LL-37 is an important part of the human immune system, which can resist various pathogens. A plethora of experiments have demonstrated that it has the multifunctional effects of immune regulation, in addition to antimicrobial activity.  Significantly boosts immune function; Fights inflammation; Prevents cancer progression; Accelerates wound healing; Lowers the risk of heart disease; Prevents lung injury; Promotes bone repair.

Side Effects

LL-37 side effects are very uncommon. LL-37 induced apparent rosacea symptoms, erythema, and telangiectasia on the skin. Side effects associated with LL-37 may include the following:
Increased inflammation
Induction of autoimmune disease
Depression
Damage to sperm surface membranes

storage

Store at -20°C

Properties of LL-37

solubility  Water: 1 mg/ml
form  A lyophilized powder
color  White to off-white
Water Solubility  Soluble to 1 mg/ml in water

Safety information for LL-37

Computed Descriptors for LL-37

InChIKey POIUWJQBRNEFGX-XAMSXPGMSA-N

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