Argireline
Synonym(s):Acetyl hexapeptide;Acetyl Hexapeptide-3;Acetyl Hexapeptide-8;Hexapeptide 3
- CAS NO.:616204-22-9
- Empirical Formula: C34H60N14O12S
- Molecular Weight: 889
- MDL number: MFCD09842097
- EINECS: 1592732-453-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-24 19:19:26
What is Argireline?
The Uses of Argireline
Argireline is an anti-wrinkle peptide. Synthetically produced and considered to be highly effective, clinical studies indicate it can reduce the depth of existing wrinkles. May be incorporated into products marketed as having a topical-BoToX. or “wrinkle-erasing” effect.
Benefits
Acetyl Hexapeptide-8 is effectivly reduce various kind of facial wrinkles;Replenish the collagen and polysaccharide, repairthe skin.Winkey patented productin China.It is recommended dosage is 3~10%.
Clinical claims and research
Argireline is a synthetic oligopeptide that emulates the sequence of SNAP-25, a type of SNARE. It has significant skin permeation, interferes with the SNARE ternary complex, and has demonstrated interference with catecholamine release from chromaffin cells. Topical use of 10% argireline resulted in a reduced depth and roughness of periorbital wrinkles in 10 healthy women. One study on 14 volunteers showed that 5% argireline reduced periorbital wrinkles by 32% in 28 days. Most recently, argireline’s efficacy has been measured in 60 Chinese women from a randomized control trial. Its total efficacy was 48.9% compared to 0% in the placebo group, and resulted in significantly decreased wrinkle roughness.
Properties of Argireline
Density | 1.54 |
storage temp. | -20°C |
solubility | water soluble |
solubility | water soluble |
pka | 4.43±0.10(Predicted) |
form | lyophilized solid |
color | white |
Safety information for Argireline
Computed Descriptors for Argireline
InChIKey | RJZNPROJTJSYLC-LLINQDLYSA-N |
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