ADRENOMEDULLIN (HUMAN)
- CAS NO.：148498-78-6
- Empirical Formula: C264H406N80O77S3
- Molecular Weight: 6028.73324
- MDL number: MFCD00211549
- Update Date: 2024-03-27 11:49:37
What is ADRENOMEDULLIN (HUMAN)?
The Uses of ADRENOMEDULLIN (HUMAN)
Peptide elicits potent hypotensive effect, comparable to calcitonin gene-related peptide. Plays a key role in regulating endometrial angiogenesis.
General Description
Adrenomedullin (ADM) human comprises of 52 amino acids and has amine group in the C-terminal tyrosine residue. It also has a N-terminal ring structure and belongs to calcitonin peptide family. ADM has vasodilatory function and is mapped to human chromosome 11p15.4. Adrenomedullin is highly expressed in endothelial cells. Adrenomedullin controls a majority of cellular processes using cyclic adenosine monophosphate (cAMP) as a messenger. It interacts with calcitonin receptor-like receptor (CRLR) and receptor activity modifying protein 2 (RAMP2). ADM contributes to invasion activity in brain tumor cell lines. ADM signalling plays a key role in tumor progression, especially in acute myeloid leukemia.
Biochem/physiol Actions
Peptide elicits potent hypotensive effect, comparable to calcitonin gene-related peptide. Plays a key role in regulating endometrial angiogenesis.
Properties of ADRENOMEDULLIN (HUMAN)
| storage temp. | -20°C |
| solubility | Soluble at 1mg/ml in 1% acetic acid |
| form | powder |
Safety information for ADRENOMEDULLIN (HUMAN)
Computed Descriptors for ADRENOMEDULLIN (HUMAN)
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-(2,4-Dimethoxybenzyl)dihydropyrimidine-2,4(1H,3H)-dione 7-Bromo-1H-indazole N-octanoyl benzotriazole 3,4-Dibenzyloxybenzaldehyde 4-Hydrazinobenzoic acid Electrolytic Iron Powder Fmoc-Val-Cit-PAB 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 4-HYDROXY BENZYL ALCOHOL 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) S-2-CHLORO PROPIONIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 1-(4-Methylphenylsulfonyl)-1H-1,2,3-benzotriazole 1-(2-Chlorobenzyl)-4-nitro-1H-pyrazole 1-(2-Nitrophenyl)-4-phenylpiperazineRelated products of tetrahydrofuran
You may like
-
Adrenomedullin 52 human CAS 148498-78-6View Details
148498-78-6 -
55441-95-7 2 2-BIS(2-HYDROXYETHOXY)-1 1-BINAPHTHYL 99%View Details
55441-95-7 -
Ste-Glu-AEEA-AEEA-OSUView Details
1169630-40-3 -
1446013-08-6 Fmoc-His-Aib-OH TFA 98%View Details
1446013-08-6 -
127464-43-1 99%View Details
127464-43-1 -
Chloro Uracil 99%View Details
1820-81-1 -
2-ETHYLPYRIDINE 100-71-0 99%View Details
100-71-0 -
13162-05-5 99%View Details
13162-05-5