Lanoconazole

Synonym(s):2-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile

CAS NO.：101530-10-3
Empirical Formula: C14H10ClN3S2
Molecular Weight: 319.83
MDL number: MFCD00865590
EINECS: 635-180-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-02 08:55:11

What is Lanoconazole?

Description

Lanoconazole is a potent antifungal imidazole launched in Japan for the treatment of dermal mycoses. Lanoconazole is reported to be an inhibitor of ergosterol biosynthesis thus altering the ultra structure of the cell wall. It exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., Penici//ium spp., and Candida spp., being particularly active against Trichophyton spp.. It is considerably more potent than other agents of the same family such as bifonazole and clotrimazole. Clinical efficacy was demonstrated by remarkable improvements in skin symptoms of the patients with tinea pedis, tinea corporis and cruis, candidiasis or tinea versicolor.

Chemical properties

Light-Yellow Crystals

Originator

Nihon Nohyaku (Japan)

The Uses of Lanoconazole

Antifungal

The Uses of Lanoconazole

Antifungal.

What are the applications of Application

Lanoconazole is an antifungal compound

Definition

ChEBI: Lanoconazole is a conazole antifungal drug and an imidazole antifungal drug.

brand name

Astat

Properties of Lanoconazole

Melting point:	141.50C
Boiling point:	477.6±55.0 °C(Predicted)
Density	1.43±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	neat
pka	3.76±0.10(Predicted)
form	Solid
color	White
CAS DataBase Reference	101530-10-3(CAS DataBase Reference)

Safety information for Lanoconazole

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..…