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HomeProduct name listMiconazole nitrate

Miconazole nitrate

Synonym(s):(±)-Miconazole nitrate salt;1-(2,4-Dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole

  • CAS NO.:22832-87-7
  • Empirical Formula: C18H15Cl4N3O4
  • Molecular Weight: 479.14
  • MDL number: MFCD00058161
  • EINECS: 245-256-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-26 17:21:34
Miconazole nitrate Structural Picture

What is Miconazole nitrate?

Description

Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14α-demethylation of lanosterol, which consequently leads to the inhibition of ergosterol synthesis in fungal cell membranes. Additionally, miconazole has been shown to induce reactive oxygen species in fungal biofilms, demonstrating a MIC value of ≥256 μM against Candida spp.

The Uses of Miconazole nitrate

Antifungal (topical).

What are the applications of Application

Miconazole Nitrate is an antifungal agent that inhibits platelet cyclooxygenase

Properties of Miconazole nitrate

Melting point: 170-185 C
Density  1.5000 (rough estimate)
storage temp.  2-8°C
solubility  pyridine: soluble50mg/mL
form  neat
color  white to off-white
Water Solubility  Slightly soluble in water. Soluble in propylene glycol or pyridine.

Safety information for Miconazole nitrate

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H317:Sensitisation, Skin
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for Miconazole nitrate

InChIKey MCCACAIVAXEFAL-UHFFFAOYSA-N

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