Mc-Val-Cit-PABC-PNP
- CAS NO.：159857-81-5
- Empirical Formula: C35H43N7O11
- Molecular Weight: 737.76
- MDL number: MFCD22200431
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is Mc-Val-Cit-PABC-PNP?
Description
Mc-Val-Cit-PABC-PNP is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). It contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to anticancer compounds, such as doxorubicin or monomethyl auristatin E (MMAE; ). ADCs target specific cell populations to induce a selective response, such as cell death in cancer cells.
The Uses of Mc-Val-Cit-PABC-PNP
Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates.
Properties of Mc-Val-Cit-PABC-PNP
| Boiling point: | 1034.5±65.0 °C(Predicted) |
| Density | 1.338±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMF: 25 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH 7.2) (1:4): 0.20 mg/ml |
| form | A crystalline solid |
| pka | 13.24±0.70(Predicted) |
| color | Off-white to light yellow |
Safety information for Mc-Val-Cit-PABC-PNP
Computed Descriptors for Mc-Val-Cit-PABC-PNP
Abamectin manufacturer
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product: 159857-81-5 98%
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