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HomeProduct name listSUC-ALA-ALA-PRO-PHE-PNA

SUC-ALA-ALA-PRO-PHE-PNA

Synonym(s):N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide;N-Succinyl-Ala-Ala-Pro-Phe-pNA;Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide - CAS 70967-97-4 - Calbiochem

SUC-ALA-ALA-PRO-PHE-PNA Structural

What is SUC-ALA-ALA-PRO-PHE-PNA?

Description

Suc-AAPF-pNA is a chromogenic substrate that can be cleaved by cathepsin G (Km = 1.7 mM), subtilisins, chymotrypsin (Km = 60 μM), chymase (Km = 4 mM), and cyclophilin, but not neutrophil elastase. Release of p-nitroanilide is monitored at 405-410 nm. This substrate can be used for inhibitor screening and kinetic analysis.

The Uses of SUC-ALA-ALA-PRO-PHE-PNA

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used as a substrate to determine chymotrypsin activity.

What are the applications of Application

Cathepsin G substrate is a substrate for quantitative determination of cathepsin G activity

Biochem/physiol Actions

N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a substrate for subtilisin and proteases.

Properties of SUC-ALA-ALA-PRO-PHE-PNA

storage temp.  -20°C
solubility  DMF: 25 mg/mL, clear, light yellow
form  White to off-white solid
color  White to off-white
BRN  4289896

Safety information for SUC-ALA-ALA-PRO-PHE-PNA

Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for SUC-ALA-ALA-PRO-PHE-PNA

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