L-Lactic dehydrogenase
Synonym(s):LAD;Lactate;LDH;LD;L-Lactate Dehydrogenase
- CAS NO.：9001-60-9
- Empirical Formula: NULL
- Molecular Weight: 0
- MDL number: MFCD00131466
- EINECS: 232-617-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is L-Lactic dehydrogenase?
The Uses of L-Lactic dehydrogenase
L-Lactic dehydrogenase is used in the determination of pyruvate (used in conjunction with reduced coenzyme) and in the diagnosis of myocardial infarction and leukemia.
The Uses of L-Lactic dehydrogenase
L-Lactic Dehydrogenase from bovine heart has been used as a standard in cytotoxicity assay. It has also been used in glutamic pyruvic transaminase (GPT) assay.
The Uses of L-Lactic dehydrogenase
L-Lactic Dehydrogenase from bovine heart has been used in ATPase assay of R2 complex Rvb1p-Rvb2p, RecA protein and sarcoplasmic reticulum Ca2+-ATPase (SERCA).
General Description
L-lactate dehydrogenase (LDH) is an enzyme that catalyzes the conversion of lactate to pyruvate.?In particular, lactic dehydrogenase A (LDHA) is mainly found in skeletal muscle, and for that reason is known as the M subunit. This recombinant form of LDHA has a C-terminal histidine-tag.
The gene LDHA (L-lactate dehydrogenase A chain) is mapped to human chromosome 11p15. It is a subunit of lactate dehydrogenase.
Biochem/physiol Actions
Also catalyzes the oxidation of other L-2-hydroxymonocarboxylic acids.
Purification Methods
A forty-fold purification of the dehydrogenase is effected by affinity chromatography using Sepharose 4B coupled to 8-(6-aminohexyl)amino-5'-AMP or -NAD . [Lees et al. Arch Biochem Biophys 163 561 1974, Pesce et al. J Biol Chem 239 1753 1964.]
Properties of L-Lactic dehydrogenase
| storage temp. | 2-8°C |
| form | suspension |
| color | white |
| Merck | 13,5349 |
| CAS DataBase Reference | 9001-60-9 |
| EPA Substance Registry System | Dehydrogenase, lactate (9001-60-9) |
Safety information for L-Lactic dehydrogenase
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for L-Lactic dehydrogenase
L-Lactic dehydrogenase manufacturer
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE 4-Bromopyrazole 5,6-Dimethoxyindanone Tert-butyl bis(2-chloroethyl)carbamate (2-Hydroxyphenyl)acetonitrile 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
Lactate Dehydrogenase, Porcine Heart CAS 9001-60-9View Details
9001-60-9 -
L-Lactic Dehydrogenase from bovine muscle CAS 9001-60-9View Details
9001-60-9 -
L-Lactic Dehydrogenase from porcine heart CAS 9001-60-9View Details
9001-60-9 -
Lactic Dehydrogenase, recombinant from E. coli CAS 9001-60-9View Details
9001-60-9 -
L-Lactic Dehydrogenase from bovine heart CAS 9001-60-9View Details
9001-60-9 -
L-Lactic Dehydrogenase from rabbit muscle CAS 9001-60-9View Details
9001-60-9 -
L-Lactic Dehydrogenase from rabbit muscle CAS 9001-60-9View Details
9001-60-9 -
L-Lactic Dehydrogenase from bovine heart CAS 9001-60-9View Details
9001-60-9