L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL

CAS NO.：19191-91-4
Empirical Formula: C24H48NO8P
Molecular Weight: 509.62
MDL number: MFCD00082429
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL?

The Uses of L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL

08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine/C8PC) has been used as a substrate to study the analytical capabilities of several methods to determine water soluble phospholipids containing choline (wCh-PL) and also to study the behavior of the its analytical signal in a synthetic serum matrix (data-Trol). It may also be used as a bicellar model to study their phase behavior and to form a lipid film to study its effect on P-glycoprotein′s (P-gp′s) activity/to compare its effect with TWEEN^?80 and Cremophor^?EL.

What are the applications of Application

1,2-Dioctanoyl PC is a synthetic substrate for PC-PLD and sPLA2

Definition

ChEBI: 1,2-dioctanoyl-sn-glycero-3-phosphocholine is a 1,2-diacyl-sn-glycero-3-phosphocholine in which the acyl groups at positions 1 and 2 are specified as octanoyl. It is a 1,2-diacyl-sn-glycero-3-phosphocholine and an octanoate ester.

General Description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Biochem/physiol Actions

Phosphatidylcholine?(PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.

Properties of L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL

storage temp.	-20°C
solubility	DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; ETOH:PBS (pH 7.2)(1:1): 0.5 mg/ml

Safety information for L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention.