1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonym(s):1,2-dicapryl-sn-glycero-3-phosphocholine; PC(10:0/10:0)
- CAS NO.:3436-44-0
- Empirical Formula: C28H56NO8P
- Molecular Weight: 565.72
- MDL number: MFCD00063538
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:01:57
What is 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE?
Description
Phosphatidylcholine species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Didecanoyl PC (DPC) is a synthetic, less hydrophobic phospholipid that has been found to be useful for enhancing the absorption of peptide drugs and hormones such as insulin. Thus, the bioavailability of intranasally applied human growth hormone is enhanced when coadministered with the absorption enhancer DPC.
The Uses of 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-Didecanoyl PC is a synthetic phospholipid.
What are the applications of Application
1,2-Didecanoyl PC is a synthetic phospholipid
Definition
ChEBI: A 1,2-diacyl-sn-glycero-3-phosphocholine in which the acyl groups at positions 1 and 2 are specified as capryl (decanoyl).
Properties of 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
storage temp. | −20°C |
solubility | Ethanol: 30 mg/ml; DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:1): 0.5 mg/ml |
BRN | 3757665 |
Safety information for 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure |
Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-CHO LINE MONOHYDRATE
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1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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