Isoprenaline sulphate
Synonym(s):Isoprenaline sulfate dihydrate
- CAS NO.:299-95-6
- Empirical Formula: 2C11H17NO3.H2O4S
- Molecular Weight: 520.6
- MDL number: MFCD00013139
- EINECS: 206-085-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-24 17:21:45
What is Isoprenaline sulphate?
Originator
Isonorin,Smith, Miller and Patch,US,1949
The Uses of Isoprenaline sulphate
Bronchodilator.
What are the applications of Application
Isoprenaline Sulfate is a useful alkaloid for biological research purposes
Manufacturing Process
As described in US Patent 2,308,232, 100 g 3,4-dihydroxy-ω-
chloroacetophenone, 200 cc ethyl alcohol and 200 cc of about 50% aqueous
isopropylamine solution are boiled during 3 hours on the water bath with the
use of a reflux condenser, whereupon neutralizing with diluted sulfuric acid is
carried out and the sulfate, obtained upon cooling, from alcohol of 50% is
recrystallized; its MP is 245°C.
21 g 3,4-dihydroxy-ω-isopropylaminoacetophenone sulfate are hydrogenated
with 50 cc methyl alcohol and 50 cc water, 0.5 g carbon and 3 cc palladium
chloride solution of 2%. After 2 hours the hydrogen absorption comes to a
standstill, after the theoretical quantity of hydrogen has been absorbed. After
concentrating, the isopropylaminomethyl-(3,4-dihydroxyphenyl)carbinolsulfate
crystallizes out. It has a MP of 180°C after refining.
brand name
Medihaler-ISO (3M Pharmaceuticals).
Therapeutic Function
Bronchodilator
Properties of Isoprenaline sulphate
Melting point: | 180 °C |
form | powder to crystal |
color | White to Almost white |
Water Solubility | almost transparency |
Safety information for Isoprenaline sulphate
Computed Descriptors for Isoprenaline sulphate
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