Indole-6-carboxylic acid
Synonym(s):6-Carboxyindole
- CAS NO.:1670-82-2
- Empirical Formula: C9H7NO2
- Molecular Weight: 161.16
- MDL number: MFCD02258929
- EINECS: 605-464-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-24 19:19:26
What is Indole-6-carboxylic acid?
Chemical properties
yellow-beige to orange-brown powder
The Uses of Indole-6-carboxylic acid
• ;Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase1• ;Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors2• ;Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway3• ;Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity4• ;Reactant for preparation of pyridinyl carboxylates via esterification with chlorohyd
The Uses of Indole-6-carboxylic acid
Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase ? Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors ? Reactant for preparation of amide conju
The Uses of Indole-6-carboxylic acid
- Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase
- Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors
- Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway
- Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity
- Reactant for preparation of pyridinyl carboxylates via esterification with chlorohydroxypyridine as SARS-CoV 3CL proinhibitors
- Reactant for preparation of (indolecarbonyl)-D-phenylglycinamide amides as factor Xa inhibitors
Synthesis Reference(s)
Journal of Medicinal Chemistry, 35, p. 2419, 1992 DOI: 10.1021/jm00091a010
Properties of Indole-6-carboxylic acid
Melting point: | 249-253 °C(lit.) |
Boiling point: | 287.44°C (rough estimate) |
Density | 1.2480 (rough estimate) |
refractive index | 1.5050 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
pka | 4.44±0.30(Predicted) |
form | Powder |
color | Yellow-beige to orange-brown |
BRN | 123991 |
CAS DataBase Reference | 1670-82-2(CAS DataBase Reference) |
Safety information for Indole-6-carboxylic acid
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Indole-6-carboxylic acid
Abamectin manufacturer
Clarity Research Laboratory
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