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HomeProduct name listIndole-5-carboxaldehyde

Indole-5-carboxaldehyde

Synonym(s):5-Formylindole

  • CAS NO.:1196-69-6
  • Empirical Formula: C9H7NO
  • Molecular Weight: 145.16
  • MDL number: MFCD02093664
  • EINECS: 627-955-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-24 19:19:26
Indole-5-carboxaldehyde Structural

What is Indole-5-carboxaldehyde?

Chemical properties

Red Crystalline Powder

The Uses of Indole-5-carboxaldehyde

Indole-5-carboxaldehyde is used as a reactant in preparation of curcumin derivatives as anti-proliferative & anti-inflammatory agents; and in synthesis of para-para stilbenophanes by McMurry coupling. It is also used as a reactant in stereoselective synthesis of dibenzylideneacetone derivatives as β-amyloid imaging probes and in structure-based drug design of aurora kinase A inhibitors.

The Uses of Indole-5-carboxaldehyde

Reactant in preparation of curcumin derivatives as anti-proliferative & anti-inflammatory agents 1 Reactant in preparation of analogs of botulinum neurotoxin serotype A protease inhibitors 2 Reactant in stereoselective synthesis of dibenzylideneacetone derivatives as β-amyloid imaging probes 3 Reactant in synthesis of para-para stilbenophanes by McMurry coupling 4 Reactant in stereoselective synthesis of heteroaromatic (E)-α,β-unsaturated ketones from aldehydes 5 Reactant in structure-based drug design of aurora kinase A inhibitors.

Properties of Indole-5-carboxaldehyde

Melting point: 100-103 °C(lit.)
Boiling point: 339.1±15.0 °C(Predicted)
Density  1.278±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  DMSO, Methanol
form  Powder
pka 16.14±0.30(Predicted)
color  Orange or tan
Water Solubility  Insoluble in water.
Sensitive  Air Sensitive
CAS DataBase Reference 1196-69-6(CAS DataBase Reference)

Safety information for Indole-5-carboxaldehyde

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Indole-5-carboxaldehyde

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