Hydrocinnamoyl chloride

Synonym(s):3-Phenylpropionyl chloride

CAS NO.：645-45-4
Empirical Formula: C9H9ClO
Molecular Weight: 168.62
MDL number: MFCD00000748
EINECS: 211-443-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-24 16:54:11

What is Hydrocinnamoyl chloride?

Chemical properties

clear colorless to light yellow liquid

The Uses of Hydrocinnamoyl chloride

Hydrocinnamoyl chloride has been used in:

enantioselective synthesis of the antifouling agent, (+)-maculalactone A
synthesis of hydrocinnamoyl-farnesyl-L-cysteine methyl ester

The Uses of Hydrocinnamoyl chloride

Hydrocinnamoyl chloride is a derivative of phenylpropionic acid used in the preparation of a wide range of pharmaceutical compounds such as antivirals and antitumor agents.

The Uses of Hydrocinnamoyl chloride

3-Phenylpropionyl Chloride is a derivative of phenylpropionic acid used in the preparation of a wide range of pharmaceutical compounds such as antivirals and antitumor agents.

General Description

Reduction of hydrocinnamoyl chloride at mercury cathodes in acetonitrile containing tetraalkylammonium perchlorates has been investigated by cyclic voltammetry.

Flammability and Explosibility

Not classified

Properties of Hydrocinnamoyl chloride

Melting point:	−7-−5 °C(lit.)
Boiling point:	107 °C11 mm Hg(lit.)
Density	1.135 g/mL at 25 °C(lit.)
vapor pressure	6.893Pa at 25℃
refractive index	n20/D 1.5265(lit.)
Flash point:	227 °F
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform (Slightly)
form	Liquid
color	deep greenish-yellow
Water Solubility	Soluble in water (reacts), and ether.
Sensitive	Moisture Sensitive
BRN	742586
CAS DataBase Reference	645-45-4(CAS DataBase Reference)
NIST Chemistry Reference	Benzenepropanoyl chloride(645-45-4)
EPA Substance Registry System	Benzenepropanoyl chloride (645-45-4)

Safety information for Hydrocinnamoyl chloride

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H315:Skin corrosion/irritation H331:Acute toxicity,inhalation H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water.