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HomeProduct name listHS-PEG8-CH2CH2COOH

HS-PEG8-CH2CH2COOH

HS-PEG8-CH2CH2COOH Structural

What is HS-PEG8-CH2CH2COOH?

Description

Thiol-PEG8-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

The Uses of HS-PEG8-CH2CH2COOH

O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol can be used:

  • To prepare near-infrared fluorochromes applicable in imaging techniques.
  • To functionalize Au nanoparticles for optoelectronic applications.
  • As a linker in the synthesis of antibody-functionalized Au nanoparticles for forensic applications.

Properties of HS-PEG8-CH2CH2COOH

Boiling point: 559.7±50.0 °C(Predicted)
Density  1.141±0.06 g/cm3(Predicted)
storage temp.  -20°C
form  Liquid
pka 4.28±0.10(Predicted)
color  Colorless to light yellow

Safety information for HS-PEG8-CH2CH2COOH

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for HS-PEG8-CH2CH2COOH

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