HS-PEG8-CH2CH2COOH
- CAS NO.：866889-02-3
- Empirical Formula: C19H38O10S
- Molecular Weight: 458.56
- MDL number: MFCD08705300
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:08
What is HS-PEG8-CH2CH2COOH?
Description
Thiol-PEG8-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
The Uses of HS-PEG8-CH2CH2COOH
O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol can be used:
- To prepare near-infrared fluorochromes applicable in imaging techniques.
- To functionalize Au nanoparticles for optoelectronic applications.
- As a linker in the synthesis of antibody-functionalized Au nanoparticles for forensic applications.
Properties of HS-PEG8-CH2CH2COOH
| Boiling point: | 559.7±50.0 °C(Predicted) |
| Density | 1.141±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| form | Liquid |
| pka | 4.28±0.10(Predicted) |
| color | Colorless to light yellow |
Safety information for HS-PEG8-CH2CH2COOH
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for HS-PEG8-CH2CH2COOH
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