Fmoc-NH-PEG3-CH2COOH
- CAS NO.：139338-72-0
- Empirical Formula: C23H27NO7
- Molecular Weight: 429.46
- MDL number: MFCD13182400
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:08
What is Fmoc-NH-PEG3-CH2COOH?
Description
Fmoc-NH-PEG3-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical properties
Fmoc-NH-PEG3-CH2COOH Appearance is colourless to light yellow viscous liquid, stored at -20℃.
The Uses of Fmoc-NH-PEG3-CH2COOH
Fmoc-9-amino-4,7-dioxanonanoic acid is an amino acid derivative and can be used as a pharmaceutical intermediate.
Properties of Fmoc-NH-PEG3-CH2COOH
| Melting point: | 46℃ |
| Boiling point: | 658.9±50.0 °C(Predicted) |
| Density | 1.248±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO |
| pka | 3.39±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for Fmoc-NH-PEG3-CH2COOH
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Fmoc-NH-PEG3-CH2COOH
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