Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listHomatropine Hydrobromide

Homatropine Hydrobromide

Synonym(s):DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide;DL-Homatropine hydrobromide;Tropine mandelate hydrobromide

  • CAS NO.:51-56-9
  • Empirical Formula: C16H22BrNO3
  • Molecular Weight: 356.25
  • MDL number: MFCD00012676
  • EINECS: 200-105-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-02 08:55:00
Homatropine Hydrobromide Structural

What is Homatropine Hydrobromide?

Description

Homatropine is an anticholinergic agent. It reduces acetylcholine-induced contractions of isolated goat detrusor muscle strips when used at a concentration of 5 μM. Homatropine (1 μM) inhibits acetylcholine- or methacholine-induced contraction of isolated rat anococcygeus muscle. It inhibits serotonin- or thrombin-induced platelet aggregation in isolated sheep platelet-rich plasma (IC50s = 4.3 and 100 μM, respectively). Topical ophthalmic administration of homatropine induces partial mydriasis in Angora goats.

Chemical properties

white crystals or crystalline powder

The Uses of Homatropine Hydrobromide

Homatropine is an anticholinergic agent. Homatropine acts as an inhibitor of the muscarinic acetylcholine receptors. Homatropine is used in eye drops as a cycloplegic and as a mydriatic, to dilate the pupil.

The Uses of Homatropine Hydrobromide

anticholinergic (opthalmic)

brand name

Isopto Homatropine (Alcon) .

General Description

Homatropine hydrobromide,1 H,5 H-tropan-3 -ol mandelate (ester) hydrobromide(Homatrocel), occurs as white crystals or as awhite, crystalline powder that is affected by light. It is solublein water (1:6) and alcohol (1:40), less soluble in chloroform(1:420), and insoluble in ether.
Solutions are incompatible with alkaline substances,which precipitate the free base, and with the commonreagents that precipitate alkaloids. As with atropine, solutionsare sterilized best by filtration through a bacteriologicalfilter.

Clinical Use

Homatropine hydrobromide is used topically to paralyzethe ciliary structure of the eye (cycloplegia) and to effectmydriasis. It behaves very much like atropine but is weakerand less toxic. In the eye, it acts more rapidly but less persistentlythan atropine. Dilation of the pupil takes place inabout 15 to 20 minutes, and the action subsides in about24 hours. By using a miotic, such as physostigmine, it ispossible to restore the pupil to normality in a few hours.

Properties of Homatropine Hydrobromide

Melting point: 214-217 °C
storage temp.  2-8°C
solubility  Freely soluble in water, sparingly soluble in alcohol.
form  neat
form  Solid
color  White to Off-White
Water Solubility  soluble
Merck  14,4730
CAS DataBase Reference 51-56-9(CAS DataBase Reference)
EPA Substance Registry System Homatropine hydrobromide (51-56-9)

Safety information for Homatropine Hydrobromide

Computed Descriptors for Homatropine Hydrobromide

Abamectin manufacturer

Otto Chemie Pvt Ltd

1Y
Phone:+91-2266382599
product: DL-Homatropine hydrobromide 98%
Inquiry

R L Fine Chem Pvt. Ltd

1Y
Phone:+91-8042488999
product: DL-Homatropine hydrobromide 98%
Inquiry

Ralington Pharma

1Y
Phone:+91-9687771722
Whatsapp: +91- 9687771722
product: DL-Homatropine hydrobromide 51-56-9 98%
Inquiry

Alcon Biosciences Pvt Ltd

Phone:+91-2261505232
product: 51-56-9 DL-Homatropine hydrobromide 99%
Inquiry

Sanvin Group of Companies (Pioneer Agro Industries)

1Y
Phone:+912261066600
product: 51-56-9 98%
Inquiry

Saurav Chemicals Ltd

1Y
Phone:+91-1725054817
product: 51-56-9 99%
Inquiry

Flowchem Pharma Pvt Ltd

1Y
Phone:+91-9845055636
Whatsapp: +91- 9845055636
product: DL-Homatropine hydrobromide 98%
Inquiry

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.