Water-18O

Synonym(s):¹⁸O Labeled water;¹⁸O Water

CAS NO.：14314-42-2
Empirical Formula: H2O
Molecular Weight: 20.02
MDL number: MFCD00064503
EINECS: 231-791-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-02 08:55:16

What is Water-18O?

Description

Only 0.2% of the oxygen-18O isotope exists in atmospheric oxygen. The Water-18O is manufactured by enriching the oxygen-18O over 98 atom% and is used to produce the [18F]FDG *1 PET diagnostic reagent for cancer. Water enriched in the oxygen-18 isotope (Water-18O) is widely used in medicine, agrochemistry and biochemistry. Oxygen-18 was first enriched to 99.5% in 1943 using thermal diffusion. To date, the use of electrolysis, chemical isotope exchange, gas diffusion, and rectification of oxygen, nitric oxide, and water has been described to enrich water with oxygen-18. Among them, the method of rectification of water, first demonstrated in 1944, is successfully used now in industry.

Chemical properties

Colourless Liquid

The Uses of Water-18O

Water-18O, 97 atom % 18O is used in DNA stable isotope probing (SIP) to investigate microbial growth and death in environmental samples.

The Uses of Water-18O

Water-¹⁸O is an isotopically modified water, which is appropriate for PET applications.
It can also be used:

In paleoclimatology, hydrology, and plant ecology to determine soil stable oxygen isotope analysis of plant cellulose using δ¹⁸O.
To determine the diffusion of moisture into crystals using secondary ion mass spectrometry (SIMS).

What are the applications of Application

Water-(18-O) (97% Isotopic Purity) is heavy-oxygen labeled water

Definition

ChEBI: A form of water consisting of two hydrogen atoms covalently bonded to an oxygen-18 atom.

Properties of Water-18O

Melting point:	0 °C(lit.)
Boiling point:	100 °C(lit.)
Density	1.11 g/mL at 20 °C(lit.)
storage temp.	Inert atmosphere,Room Temperature
form	Colourless Liquid
color	Colorless to light yellow
Stability:	Hygroscopic
InChI	InChI=1S/H2O/h1H2/i1+2