Guaiacol glycidyl ether
Synonym(s):(±)-2-[(2-Methoxyphenoxy)methyl]oxirane;NSC 112256;NSC 133442
- CAS NO.：2210-74-4
- Empirical Formula: C10H12O3
- Molecular Weight: 180.2
- MDL number: MFCD00190158
- EINECS: 218-644-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-31 18:15:48
What is Guaiacol glycidyl ether?
Chemical properties
White Crystalline Solid,soluble in chloroform, methanol.
The Uses of Guaiacol glycidyl ether
Guaiacol glycidyl ether is widely used as an intermediate of ranolazine and motoprol.
Flammability and Explosibility
Non flammable
Synthesis
Guaiacol and epichlorohydrin are reacted in the presence of an inorganic alkali aqueous solution and a phase transfer catalyst; thereafter, the crude guaiacol glycidyl ether is obtained by distilling under reduced pressure; the crude guaiacol glycidyl ether is recrystallizated by lower alcohol to obtain guaiacol glycidyl ether with a purity over 99.5%.
Properties of Guaiacol glycidyl ether
| Melting point: | 33-36°C |
| Boiling point: | 152-158℃ |
| Density | 1.142±0.06 g/cm3(Predicted) |
| RTECS | TZ3550000 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Chloroform, Methanol |
| form | Solid |
| color | Off-white |
| Water Solubility | 4.21g/L at 20℃ |
| CAS DataBase Reference | 2210-74-4(CAS DataBase Reference) |
Safety information for Guaiacol glycidyl ether
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Guaiacol glycidyl ether
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