Gonadorelin acetate
Synonym(s):Gonadoliberin;Gonadotropin releasing hormone;LH-RH
- CAS NO.:71447-49-9
- Empirical Formula: C57H79N17O15
- Molecular Weight: 1242.36
- MDL number: MFCD00133489
- EINECS: 636-116-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-20 11:03:12
What is Gonadorelin acetate?
The Uses of Gonadorelin acetate
Luteinizing hormone releasing hormone human acetate salt has been used:
- for synchronization of the ovulations
- for pre-absorption of the anti-GnRH antibody in staining procedures
- to study pituitary sensitivity to GnRH in presence of endocrine disrupting compound
What are the applications of Application
Gonadorelin acetate is widely used in the diagnosis of central precocious puberty.
Biochem/physiol Actions
Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.
Side Effects
Gonadorelin acetate is usually considered a safe medication. However, severe anaphylactic shock may occur after intravenous administration, manifested by loss of consciousness and tonic convulsions of the arms and legs; prompt treatment with epinephrine, diphenhydramine and fluids restores vital signs within 30 minutes. Therefore, it is recommended that these drugs be administered in an environment that is capable of handling systemic reactions.
Properties of Gonadorelin acetate
storage temp. | −20°C |
solubility | H2O: 25 mg/mL, clear, faintly yellow |
form | powder |
Safety information for Gonadorelin acetate
Signal word | Danger |
Pictogram(s) |
Health Hazard GHS08 |
GHS Hazard Statements |
H360:Reproductive toxicity |
Precautionary Statement Codes |
P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for Gonadorelin acetate
Gonadorelin acetate manufacturer
Ralington Pharma
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