Ginsenoside Rg2
Synonym(s):(3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L -mannopyranosyl)-β-D -glucopyranoside;Chikusetsusaponin I;Panaxoside Rg2;Prosapogenin C2
- CAS NO.:52286-74-5
- Empirical Formula: C42H72O13
- Molecular Weight: 785.03
- MDL number: MFCD00210511
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 18:09:03
What is Ginsenoside Rg2?
Description
Ginsenosides are pharmacologically active natural compounds from ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rg2 is a protopanaxatriol that is more abundant in some Panax species (e.g., white and red P. ginseng) than others. This ginsenoside and its metabolites have diverse in vitro and in vivo effects, including neuroprotective, anti-
Chemical properties
White solid
The Uses of Ginsenoside Rg2
20(S)-Ginsenoside Rg2 is used as an aldose reductase inhibitor and my exert anti-inflammatory and immunomodulatory activity. It exists as a bioactive metabolite of the ginsenoside component of Panax ginseng.
What are the applications of Application
Ginsenoside Rg2 is an antiproliferative agent
Definition
ChEBI: Ginsenoside Rg2 is a ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, a cardioprotective agent and an anticoagulant. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a ginsenoside, a tetracyclic triterpenoid, a disaccharide derivative, a 20-hydroxy steroid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.
Properties of Ginsenoside Rg2
Melting point: | 187~189℃ |
Boiling point: | 881.0±65.0 °C(Predicted) |
Density | 1.30±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Methanol (Slightly, Heated, Sonicated), Pyridine (Slightly, Sonicated) |
form | Solid |
pka | 12.85±0.70(Predicted) |
color | White to Off-White |
Stability: | Hygroscopic |
Safety information for Ginsenoside Rg2
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for Ginsenoside Rg2
InChIKey | AGBCLJAHARWNLA-DJZXLMSJSA-N |
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