Ginsenoside Rd
Synonym(s):(3β,12β)-20-(β-D -Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D -glucopyranosyl-β-D -glucopyranoside;Gypenoside VIII
- CAS NO.:52705-93-8
- Empirical Formula: C48H82O18
- Molecular Weight: 947.15
- MDL number: MFCD00799993
- EINECS: 258-118-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-31 18:15:48
What is Ginsenoside Rd?
Description
Ginsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rd is a protopanaxadiol which is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-
Chemical properties
White to off-white crystals powder
The Uses of Ginsenoside Rd
Ginsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia.
What are the applications of Application
Ginsenoside Rd is a compound that may inhibit or prevent tumor growth
Definition
ChEBI: Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. It has a role as a vulnerary, a neuroprotective agent, an apoptosis inducer, an anti-inflammatory drug, an immunosuppressive agent and a plant metabolite. It is a ginsenoside, a beta-D-glucoside and a tetracyclic triterpenoid. It is functionally related to a (20S)-ginsenoside Rg3.
Properties of Ginsenoside Rd
Melting point: | 204~206℃ |
Boiling point: | 1015.6±65.0 °C(Predicted) |
Density | 1.38±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 12.85±0.70(Predicted) |
color | White to Off-White |
Stability: | Hygroscopic |
CAS DataBase Reference | 52705-93-8(CAS DataBase Reference) |
Safety information for Ginsenoside Rd
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for Ginsenoside Rd
InChIKey | FBFMBWCLBGQEBU-FIKSETHBNA-N |
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