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HomeProduct name listGinsenoside Rd

Ginsenoside Rd

Synonym(s):(3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside;Gypenoside VIII

  • CAS NO.:52705-93-8
  • Empirical Formula: C48H82O18
  • Molecular Weight: 947.15
  • MDL number: MFCD00799993
  • EINECS: 258-118-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-31 18:15:48
Ginsenoside Rd Structural

What is Ginsenoside Rd?

Description

Ginsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rd is a protopanaxadiol which is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions. Notably, ginsenoside Rd is converted to other ginsenosides in response to steaming or heating plant materials, leading to loss of these activities.

Chemical properties

White to off-white crystals powder

The Uses of Ginsenoside Rd

Ginsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia.

What are the applications of Application

Ginsenoside Rd is a compound that may inhibit or prevent tumor growth

Definition

ChEBI: Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. It has a role as a vulnerary, a neuroprotective agent, an apoptosis inducer, an anti-inflammatory drug, an immunosuppressive agent and a plant metabolite. It is a ginsenoside, a beta-D-glucoside and a tetracyclic triterpenoid. It is functionally related to a (20S)-ginsenoside Rg3.

Properties of Ginsenoside Rd

Melting point: 204~206℃
Boiling point: 1015.6±65.0 °C(Predicted)
Density  1.38±0.1 g/cm3(Predicted)
storage temp.  Inert atmosphere,2-8°C
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 12.85±0.70(Predicted)
color  White to Off-White
Stability: Hygroscopic
CAS DataBase Reference 52705-93-8(CAS DataBase Reference)

Safety information for Ginsenoside Rd

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501:Dispose of contents/container to..…

Computed Descriptors for Ginsenoside Rd

InChIKey FBFMBWCLBGQEBU-FIKSETHBNA-N

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