FUMITREMORGIN C
Synonym(s):Fumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem;NSC719655, FTC
- CAS NO.:118974-02-0
- Empirical Formula: C22H25N3O3
- Molecular Weight: 379.45
- MDL number: MFCD08702652
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-20 11:41:24
What is FUMITREMORGIN C?
The Uses of FUMITREMORGIN C
Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter.
The Uses of FUMITREMORGIN C
Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter.
What are the applications of Application
Fumitremorgin C is a strong and specific BRCP inhibitor
Definition
ChEBI: An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi. A potent and specific inhibitor of the breast cancer resistance protein multidrug transporter.
General Description
A cell-permeable indolyldiketopiperazinyl mycotoxin that inhibits BCRP/ABCG2 (breast cancer resistance protein/ATP-binding cassette G2) multidrug transport activity. Also acts as a potent and specific chemosenzitizing agent.
Biochem/physiol Actions
Cell permeable: yes
storage
+4°C
Properties of FUMITREMORGIN C
Melting point: | 259.5-260.5℃ |
Boiling point: | 642.9±55.0 °C(Predicted) |
Density | 1.34±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | acetonitrile: 5 mg/mL, soluble |
form | solid |
pka | 17.16±0.40(Predicted) |
color | White to light brown |
Safety information for FUMITREMORGIN C
Computed Descriptors for FUMITREMORGIN C
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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