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HomeProduct name listFUMITREMORGIN C

FUMITREMORGIN C

Synonym(s):Fumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem;NSC719655, FTC

FUMITREMORGIN C Structural

What is FUMITREMORGIN C?

The Uses of FUMITREMORGIN C

Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter.

The Uses of FUMITREMORGIN C

Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter.

What are the applications of Application

Fumitremorgin C is a strong and specific BRCP inhibitor

Definition

ChEBI: An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi. A potent and specific inhibitor of the breast cancer resistance protein multidrug transporter.

General Description

A cell-permeable indolyldiketopiperazinyl mycotoxin that inhibits BCRP/ABCG2 (breast cancer resistance protein/ATP-binding cassette G2) multidrug transport activity. Also acts as a potent and specific chemosenzitizing agent.

Biochem/physiol Actions

Cell permeable: yes

storage

+4°C

Properties of FUMITREMORGIN C

Melting point: 259.5-260.5℃
Boiling point: 642.9±55.0 °C(Predicted)
Density  1.34±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  acetonitrile: 5 mg/mL, soluble
form  solid
pka 17.16±0.40(Predicted)
color  White to light brown

Safety information for FUMITREMORGIN C

Computed Descriptors for FUMITREMORGIN C

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