Formylhydrazine

Synonym(s):Formic acid hydrazide;Formylhydrazine

CAS NO.：624-84-0
Empirical Formula: CH4N2O
Molecular Weight: 60.06
MDL number: MFCD00007589
EINECS: 210-867-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-15 16:24:08

What is Formylhydrazine?

Chemical properties

WHITE SHINY CRYSTALLINE FLAKES

The Uses of Formylhydrazine

Formic acid hydrazide is used as a precursor in the preparation of 1,2,4-triazole derivatives. It is also used in the synthesis of 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7(6H)-dione, which is an anticancer agent.

Purification Methods

Recrystallise it from EtOH and dry it in vacuo. Store below 10o; it may disproportionate on storage to 1,2-diformyl hydrazine and hydrazine. It forms a blue [Cu(CH4N2O)]SO4 salt with CuSO4. [Beilstein 2 H 93, 2 III 127, 2 IV 85.]

Properties of Formylhydrazine

Melting point:	52-57 °C (lit.)
Boiling point:	90°C/0.7mmHg(lit.)
Density	1.094±0.06 g/cm3(Predicted)
refractive index	1.4840 (estimate)
Flash point:	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	water: soluble2.5%, clear, colorless
form	Shiny Crystalline Flakes
pka	13.65±0.20(Predicted)
color	White
Water Solubility	Soluble
Sensitive	Hygroscopic
BRN	635759
CAS DataBase Reference	624-84-0(CAS DataBase Reference)
NIST Chemistry Reference	Formic acid hydrazide(624-84-0)
EPA Substance Registry System	Hydrazinecarboxaldehyde (624-84-0)

Safety information for Formylhydrazine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.