FMoc-Val-Cit-PAB
- CAS NO.：159858-22-7
- Empirical Formula: C33H39N5O6
- Molecular Weight: 601.69
- MDL number: MFCD22417106
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-24 15:44:31
What is FMoc-Val-Cit-PAB?
Description
Fmoc-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Fmoc can be deprotected under basic condition.
Properties of FMoc-Val-Cit-PAB
| Melting point: | 204 °C(dec.) |
| Boiling point: | 914.2±65.0 °C(Predicted) |
| Density | 1.276±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| form | powder to crystal |
| pka | 10.63±0.46(Predicted) |
| color | White to Almost white |
| CAS DataBase Reference | 159858-22-7 |
Safety information for FMoc-Val-Cit-PAB
Computed Descriptors for FMoc-Val-Cit-PAB
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